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Modeling the prevalence of immunodeficiency-associated long-term vaccine-derived poliovirus excretors and the potential benefits of antiviral drugs

BACKGROUND: A small number of individuals with B-cell-related primary immunodeficiency diseases (PIDs) may exhibit long-term (prolonged or chronic) excretion of immunodeficiency-associated vaccine-derived polioviruses (iVDPVs) following infection with oral poliovirus vaccine (OPV). These individuals...

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Detalles Bibliográficos
Autores principales: Duintjer Tebbens, Radboud J., Pallansch, Mark A., Thompson, Kimberly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574619/
https://www.ncbi.nlm.nih.gov/pubmed/26382043
http://dx.doi.org/10.1186/s12879-015-1115-5