Statins Increase Plasminogen Activator Inhibitor Type 1 Gene Transcription through a Pregnane X Receptor Regulated Element

Plasminogen activator inhibitor type 1 (PAI-1) is a multifunctional protein that has important roles in inflammation and wound healing. Its aberrant regulation may contribute to many disease processes such as heart disease. The PAI-1 promoter is responsive to multiple inputs including cytokines, gro...

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Detalles Bibliográficos
Autores principales: Stanley, Frederick M., Linder, Kathryn M., Cardozo, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574702/
https://www.ncbi.nlm.nih.gov/pubmed/26379245
http://dx.doi.org/10.1371/journal.pone.0138097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574702/
https://www.ncbi.nlm.nih.gov/pubmed/26379245
http://dx.doi.org/10.1371/journal.pone.0138097

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