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Des-Aspartate-Angiotensin I Attenuates Mortality of Mice Exposed to Gamma Radiation via a Novel Mechanism of Action

ACE inhibitors and ARBs (angiotensin receptor blockers) have been shown to attenuate radiation injuries in animal models of lethal gamma irradiation. These two classes of drug act by curtailing the actions of angiotensin II-linked inflammatory pathways that are up-regulated during gamma radiation in...

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Detalles Bibliográficos
Autores principales: Wang, Hong, Sethi, Gautam, Loke, Weng-Keong, Sim, Meng-Kwoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574738/
https://www.ncbi.nlm.nih.gov/pubmed/26378927
http://dx.doi.org/10.1371/journal.pone.0138009