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The use of duplex-specific nuclease in ribosome profiling and a user-friendly software package for Ribo-seq data analysis

Ribosome profiling is a technique that permits genome-wide, quantitative analysis of translation and has found broad application in recent years. Here we describe a modified profiling protocol and software package designed to benefit more broadly the translation community in terms of simplicity and...

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Detalles Bibliográficos
Autores principales: Chung, Betty Y., Hardcastle, Thomas J., Jones, Joshua D., Irigoyen, Nerea, Firth, Andrew E., Baulcombe, David C., Brierley, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574750/
https://www.ncbi.nlm.nih.gov/pubmed/26286745
http://dx.doi.org/10.1261/rna.052548.115