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Altered CELF1 binding to target transcripts in malignant T cells

The RNA-binding protein, CELF1, binds to a regulatory sequence known as the GU-rich element (GRE) and controls a network of mRNA transcripts that regulate cellular activation, proliferation, and apoptosis. We performed immunoprecipitation using an anti-CELF1 antibody, followed by identification of c...

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Detalles Bibliográficos
Autores principales: Bohjanen, Paul R., Moua, Mai Lee, Guo, Liang, Taye, Ammanuel, Vlasova-St. Louis, Irina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574752/
https://www.ncbi.nlm.nih.gov/pubmed/26249002
http://dx.doi.org/10.1261/rna.049940.115