In vivo analysis of trypanosome mitochondrial RNA function by artificial site-specific RNA endonuclease-mediated knockdown

Trypanosomes possess a unique mitochondrial genome called the kinetoplast DNA (kDNA). Many kDNA genes encode pre-mRNAs that must undergo guide RNA-directed editing. In addition, alternative mRNA editing gives rise to diverse mRNAs and several kDNA genes encode open reading frames of unknown function...

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Detalles Bibliográficos
Autores principales: Szempruch, Anthony J., Choudhury, Rajarshi, Wang, Zefeng, Hajduk, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574754/
https://www.ncbi.nlm.nih.gov/pubmed/26264591
http://dx.doi.org/10.1261/rna.052084.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574754/
https://www.ncbi.nlm.nih.gov/pubmed/26264591
http://dx.doi.org/10.1261/rna.052084.115

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