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eIF4AII is dispensable for miRNA-mediated gene silencing

MicroRNAs (miRNAs) are short noncoding RNAs that regulate gene expression through partial complementary base-pairing to the 3′ untranslated region (UTR) of target mRNAs. Inhibition of translation initiation has been identified as an early event of miRNA-mediated gene repression, but the underlying m...

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Detalles Bibliográficos
Autores principales: Galicia-Vázquez, Gabriela, Chu, Jennifer, Pelletier, Jerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574758/
https://www.ncbi.nlm.nih.gov/pubmed/26286746
http://dx.doi.org/10.1261/rna.052225.115