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B Cells and Programmed Death-Ligand 2 Signaling Are Required for Maximal Interferon-γ Recall Response by Splenic CD4(+) Memory T Cells of Mice Vaccinated with Mycobacterium tuberculosis Ag85B
CD4(+) T cells producing interferon-γ are crucial for protection against Mycobacterium tuberculosis infection and are the cornerstone of tuberculosis vaccination and immunological diagnostic assays. Since emerging evidence indicates that B cells can modulate T cell responses to M. tuberculosis infec...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574766/ https://www.ncbi.nlm.nih.gov/pubmed/26379242 http://dx.doi.org/10.1371/journal.pone.0137783 |