Cargando…

Activation and reactivation of the RNA polymerase II trigger loop for intrinsic RNA cleavage and catalysis

In addition to RNA synthesis, multisubunit RNA polymerases (msRNAPs) support enzymatic reactions such as intrinsic transcript cleavage. msRNAP active sites from different species appear to exhibit differential intrinsic transcript cleavage efficiency and have likely evolved to allow fine-tuning of t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Čabart, Pavel, Jin, Huiyan, Li, Liangtao, Kaplan, Craig D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574878/ https://www.ncbi.nlm.nih.gov/pubmed/25764335 http://dx.doi.org/10.4161/trns.28869

Ejemplares similares

High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop
por: Qiu, Chenxi, et al.
Publicado: (2016)

Correction: High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop
por: Qiu, Chenxi, et al.
Publicado: (2018)

Interplay between the trigger loop and the F loop during RNA polymerase catalysis
por: Miropolskaya, Nataliya, et al.
Publicado: (2014)

Characterization of RNA polymerase II trigger loop mutations using molecular dynamics simulations and machine learning
por: Dutagaci, Bercem, et al.
Publicado: (2023)

Relationships of RNA Polymerase II Genetic Interactors to Transcription Start Site Usage Defects and Growth in Saccharomyces cerevisiae
por: Jin, Huiyan, et al.
Publicado: (2014)

Closing and opening of the RNA polymerase trigger loop
por: Mazumder, Abhishek, et al.
Publicado: (2020)

Intrinsic Cleavage of RNA Polymerase II Adopts a Nucleobase-independent Mechanism Assisted by Transcript Phosphate
por: Ka Man Tse, Carmen, et al.
Publicado: (2019)

Dissection of Pol II Trigger Loop Function and Pol II Activity–Dependent Control of Start Site Selection In Vivo
por: Kaplan, Craig D., et al.
Publicado: (2012)

Relationships Between RNA Polymerase II Activity and Spt Elongation Factors to Spt(-) Phenotype and Growth in Saccharomyces cerevisiae
por: Cui, Ping, et al.
Publicado: (2016)

“Bind, cleave and leave”: multiple turnover catalysis of RNA cleavage by bulge–loop inducing supramolecular conjugates
por: Amirloo, Bahareh, et al.
Publicado: (2021)

Lineage-specific variations in the trigger loop modulate RNA proofreading by bacterial RNA polymerases
por: Esyunina, Daria, et al.
Publicado: (2016)

Bridge helix and trigger loop perturbations generate superactive RNA polymerases
por: Tan, Lin, et al.
Publicado: (2008)

Evidence that Transcript Cleavage Is Essential for RNA Polymerase II Transcription and Cell Viability
por: Sigurdsson, Stefan, et al.
Publicado: (2010)

Mediator is an intrinsic component of the basal RNA polymerase II machinery in vivo
por: Lacombe, Thierry, et al.
Publicado: (2013)

The RNA polymerase trigger loop functions in all three phases of the transcription cycle
por: Fouqueau, Thomas, et al.
Publicado: (2013)

Two distinct pathways of RNA polymerase backtracking determine the requirement for the Trigger Loop during RNA hydrolysis
por: Mosaei, Hamed, et al.
Publicado: (2021)

The architecture of RNA polymerase fidelity
por: Kaplan, Craig D
Publicado: (2010)

Splicing- and cleavage-independent requirement of RNA polymerase II CTD for mRNA release from the transcription site
por: Custódio, Noélia, et al.
Publicado: (2007)

Controlled interplay between trigger loop and Gre factor in the RNA polymerase active centre
por: Roghanian, Mohammad, et al.
Publicado: (2011)

Structural heterogeneity in the intrinsically disordered RNA polymerase II C-terminal domain
por: Portz, Bede, et al.
Publicado: (2017)

AT-rich sequence elements promote nascent transcript cleavage leading to RNA polymerase II termination
por: White, Eleanor, et al.
Publicado: (2013)

Widespread epistasis shapes RNA Polymerase II active site function and evolution
por: Duan, Bingbing, et al.
Publicado: (2023)

Trigger-helix folding pathway and SI3 mediate catalysis and hairpin-stabilized pausing by Escherichia coli RNA polymerase
por: Windgassen, Tricia A., et al.
Publicado: (2014)

RNA Polymerase II Mutations Conferring Defects in Poly(A) Site Cleavage and Termination in Saccharomyces cerevisiae
por: Kubicek, Charles E., et al.
Publicado: (2013)

Fast ribozyme cleavage releases transcripts from RNA polymerase II and aborts co-transcriptional pre-mRNA processing
por: Fong, Nova, et al.
Publicado: (2009)

Dissecting the chemical interactions and substrate structural signatures governing RNA polymerase II trigger loop closure by synthetic nucleic acid analogues
por: Xu, Liang, et al.
Publicado: (2014)

A bridge to transcription by RNA polymerase
por: Kaplan, Craig D, et al.
Publicado: (2008)

Enhanced RNA cleavage within bulge-loops by an artificial ribonuclease
por: Kuznetsova, Irina L., et al.
Publicado: (2005)

RNA Folding and Catalysis Mediated by Iron (II)
por: Athavale, Shreyas S., et al.
Publicado: (2012)

Evolution of the RNA Cleavage Subunit C11/RPC10, and Recycling by RNA Polymerase III
por: Mishra, Saurabh, et al.
Publicado: (2022)

RNAs nonspecifically inhibit RNA polymerase II by preventing binding to the DNA template
por: Pai, Dave A., et al.
Publicado: (2014)

RNA polymerases as moving barriers to condensin loop extrusion
por: Brandão, Hugo B., et al.
Publicado: (2019)

BRCA2 Regulates Transcription Elongation by RNA Polymerase II to Prevent R-Loop Accumulation
por: Shivji, Mahmud K.K., et al.
Publicado: (2018)

RNA polymerase II depletion promotes transcription of alternative mRNA species
por: Yu, Lijian, et al.
Publicado: (2016)

Attenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis
por: Zhang, Xiaowen, et al.
Publicado: (2017)

Extragenic Accumulation of RNA Polymerase II Enhances Transcription by RNA Polymerase III
por: Listerman, Imke, et al.
Publicado: (2007)

Catalysis of Template-Directed Nonenzymatic RNA Copying by Iron(II)
por: Jin, Lin, et al.
Publicado: (2018)

Nucleotide addition and cleavage by RNA polymerase II: Coordination of two catalytic reactions using a single active site
por: Unarta, Ilona Christy, et al.
Publicado: (2022)

Co-transcriptional RNA cleavage provides a failsafe termination mechanism for yeast RNA polymerase I
por: Braglia, Priscilla, et al.
Publicado: (2011)

Crosslinking-MS analysis reveals RNA polymerase I domain architecture and basis of rRNA cleavage
por: Jennebach, Stefan, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_btfu8uk9re6l40qkt56v5ga6kg