CD44 Binding to Hyaluronic Acid Is Redox Regulated by a Labile Disulfide Bond in the Hyaluronic Acid Binding Site

CD44 is the primary leukocyte cell surface receptor for hyaluronic acid (HA), a component of the extracellular matrix. Enzymatic post translational cleavage of labile disulfide bonds is a mechanism by which proteins are structurally regulated by imparting an allosteric change and altering activity....

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Detalles Bibliográficos
Autores principales: Kellett-Clarke, Helena, Stegmann, Monika, Barclay, A. Neil, Metcalfe, Clive
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574955/
https://www.ncbi.nlm.nih.gov/pubmed/26379032
http://dx.doi.org/10.1371/journal.pone.0138137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574955/
https://www.ncbi.nlm.nih.gov/pubmed/26379032
http://dx.doi.org/10.1371/journal.pone.0138137

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