Decline of Phosphotransfer and Substrate Supply Metabolic Circuits Hinders ATP Cycling in Aging Myocardium

Integration of mitochondria with cytosolic ATP-consuming/ATP-sensing and substrate supply processes is critical for muscle bioenergetics and electrical activity. Whether age-dependent muscle weakness and increased electrical instability depends on perturbations in cellular energetic circuits is unkn...

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Detalles Bibliográficos
Autores principales: Nemutlu, Emirhan, Gupta, Anu, Zhang, Song, Viqar, Maria, Holmuhamedov, Ekhson, Terzic, Andre, Jahangir, Arshad, Dzeja, Petras
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574965/
https://www.ncbi.nlm.nih.gov/pubmed/26378442
http://dx.doi.org/10.1371/journal.pone.0136556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574965/
https://www.ncbi.nlm.nih.gov/pubmed/26378442
http://dx.doi.org/10.1371/journal.pone.0136556

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