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Decline of Phosphotransfer and Substrate Supply Metabolic Circuits Hinders ATP Cycling in Aging Myocardium

Integration of mitochondria with cytosolic ATP-consuming/ATP-sensing and substrate supply processes is critical for muscle bioenergetics and electrical activity. Whether age-dependent muscle weakness and increased electrical instability depends on perturbations in cellular energetic circuits is unkn...

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Detalles Bibliográficos
Autores principales:	Nemutlu, Emirhan, Gupta, Anu, Zhang, Song, Viqar, Maria, Holmuhamedov, Ekhson, Terzic, Andre, Jahangir, Arshad, Dzeja, Petras
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574965/ https://www.ncbi.nlm.nih.gov/pubmed/26378442 http://dx.doi.org/10.1371/journal.pone.0136556

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