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A Multi-Marker Genetic Association Test Based on the Rasch Model Applied to Alzheimer’s Disease
Results from Genome-Wide Association Studies (GWAS) have shown that the genetic basis of complex traits often include many genetic variants with small to moderate effects whose identification remains a challenging problem. In this context multi-marker analysis at the gene and pathway level can compl...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574966/ https://www.ncbi.nlm.nih.gov/pubmed/26379234 http://dx.doi.org/10.1371/journal.pone.0138223 |