Cargando…

A Multi-Marker Genetic Association Test Based on the Rasch Model Applied to Alzheimer’s Disease

Results from Genome-Wide Association Studies (GWAS) have shown that the genetic basis of complex traits often include many genetic variants with small to moderate effects whose identification remains a challenging problem. In this context multi-marker analysis at the gene and pathway level can compl...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Wenjia, Mandel, Jonas, Bouaziz, Jan, Commenges, Daniel, Nabirotchkine, Serguei, Chumakov, Ilya, Cohen, Daniel, Guedj, Mickaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574966/
https://www.ncbi.nlm.nih.gov/pubmed/26379234
http://dx.doi.org/10.1371/journal.pone.0138223