Cargando…
A Multi-Marker Genetic Association Test Based on the Rasch Model Applied to Alzheimer’s Disease
Results from Genome-Wide Association Studies (GWAS) have shown that the genetic basis of complex traits often include many genetic variants with small to moderate effects whose identification remains a challenging problem. In this context multi-marker analysis at the gene and pathway level can compl...
Autores principales: | Wang, Wenjia, Mandel, Jonas, Bouaziz, Jan, Commenges, Daniel, Nabirotchkine, Serguei, Chumakov, Ilya, Cohen, Daniel, Guedj, Mickaël |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574966/ https://www.ncbi.nlm.nih.gov/pubmed/26379234 http://dx.doi.org/10.1371/journal.pone.0138223 |
Ejemplares similares
-
A Rasch Analysis of the Charcot-Marie-Tooth Neuropathy Score (CMTNS) in a Cohort of Charcot-Marie-Tooth Type 1A Patients
por: Wang, Wenjia, et al.
Publicado: (2017) -
A meta-analysis of randomized double-blind clinical trials in CMT1A to assess the change from baseline in CMTNS and ONLS scales after one year of treatment
por: Mandel, Jonas, et al.
Publicado: (2015) -
Estimation of dynamical model parameters taking into account undetectable marker values
por: Thiébaut, Rodolphe, et al.
Publicado: (2006) -
Combination of acamprosate and baclofen as a promising therapeutic approach for Parkinson’s disease
por: Hajj, Rodolphe, et al.
Publicado: (2015) -
Combining two repurposed drugs as a promising approach for Alzheimer's disease therapy
por: Chumakov, Ilya, et al.
Publicado: (2015)