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Magnetic Resonance Imaging Is Sensitive to Pathological Amelioration in a Model for Laminin-Deficient Congenital Muscular Dystrophy (MDC1A)

PURPOSE: To elucidate the reliability of MRI as a non-invasive tool for assessing in vivo muscle health and pathological amelioration in response to Losartan (Angiotensin II Type 1 receptor blocker) in DyW mice (mouse model for Laminin-deficient Congenital Muscular Dystrophy Type 1A). METHODS: Multi...

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Detalles Bibliográficos
Autores principales: Vohra, Ravneet, Accorsi, Anthony, Kumar, Ajay, Walter, Glenn, Girgenrath, Mahasweta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575026/
https://www.ncbi.nlm.nih.gov/pubmed/26379183
http://dx.doi.org/10.1371/journal.pone.0138254