Cargando…

Magnetic Resonance Imaging Is Sensitive to Pathological Amelioration in a Model for Laminin-Deficient Congenital Muscular Dystrophy (MDC1A)

PURPOSE: To elucidate the reliability of MRI as a non-invasive tool for assessing in vivo muscle health and pathological amelioration in response to Losartan (Angiotensin II Type 1 receptor blocker) in DyW mice (mouse model for Laminin-deficient Congenital Muscular Dystrophy Type 1A). METHODS: Multi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vohra, Ravneet, Accorsi, Anthony, Kumar, Ajay, Walter, Glenn, Girgenrath, Mahasweta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575026/ https://www.ncbi.nlm.nih.gov/pubmed/26379183 http://dx.doi.org/10.1371/journal.pone.0138254

Ejemplares similares

Dysregulation of matricellular proteins is an early signature of pathology in laminin-deficient muscular dystrophy
por: Mehuron, Thomas, et al.
Publicado: (2014)

Correction: dysregulation of matricellular proteins is an early signature of pathology in laminin-deficient muscular dystrophy
por: Mehuron, Thomas, et al.
Publicado: (2014)

Fibrogenesis in LAMA2-Related Muscular Dystrophy Is a Central Tenet of Disease Etiology
por: Accorsi, Anthony, et al.
Publicado: (2020)

Angiotensin II type 1 receptor antagonists alleviate muscle pathology in the mouse model for laminin-α2-deficient congenital muscular dystrophy (MDC1A)
por: Meinen, Sarina, et al.
Publicado: (2012)

Improving Reproducibility of Phenotypic Assessments in the DyW Mouse Model of Laminin-α2 Related Congenital Muscular Dystrophy
por: Willmann, Raffaella, et al.
Publicado: (2017)

Cobblestone Malformation in LAMA2 Congenital Muscular Dystrophy (MDC1A)
por: Jayakody, Himali, et al.
Publicado: (2020)

Zebrafish Models of LAMA2-Related Congenital Muscular Dystrophy (MDC1A)
por: Fabian, Lacramioara, et al.
Publicado: (2020)

Linker molecules between laminins and dystroglycan ameliorate laminin-α2–deficient muscular dystrophy at all disease stages
por: Meinen, Sarina, et al.
Publicado: (2007)

Widening the spectrum of LAMA 2 congenital muscular dystrophy (MDC1A): cobblestone malformation
por: Borella, Luiz Fernando Monte, et al.
Publicado: (2021)

Current understanding and treatment of cardiac and skeletal muscle pathology in laminin-α2 chain-deficient congenital muscular dystrophy
por: Nguyen, Quynh, et al.
Publicado: (2019)

Contrast-Enhanced Near-Infrared Optical Imaging Detects Exacerbation and Amelioration of Murine Muscular Dystrophy
por: Chrzanowski, Stephen M., et al.
Publicado: (2017)

Diseased muscles that lack dystrophin or laminin-α2 have altered compositions and proliferation of mononuclear cell populations
por: Girgenrath, Mahasweta, et al.
Publicado: (2005)

Laminin and Integrin in LAMA2-Related Congenital Muscular Dystrophy: From Disease to Therapeutics
por: Barraza-Flores, Pamela, et al.
Publicado: (2020)

Skeletal muscle laminin and MDC1A: pathogenesis and treatment strategies
por: Gawlik, Kinga I, et al.
Publicado: (2011)

Natural disease history of the dy(2J) mouse model of laminin α2 (merosin)-deficient congenital muscular dystrophy
por: Pasteuning-Vuhman, S., et al.
Publicado: (2018)

Antioxidants Reduce Muscular Dystrophy in the dy(2J)/dy(2J) Mouse Model of Laminin α2 Chain-Deficient Muscular Dystrophy
por: Harandi, Vahid M., et al.
Publicado: (2020)

Early skeletal muscle pathology and disease progress in the dy(3K)/dy(3K) mouse model of congenital muscular dystrophy with laminin α2 chain-deficiency
por: Gawlik, Kinga I., et al.
Publicado: (2019)

miR-410 and miR-495 Are Dynamically Regulated in Diverse Cardiomyopathies and Their Inhibition Attenuates Pathological Hypertrophy
por: Clark, Amanda L., et al.
Publicado: (2016)

Long-term follow-up of laminin α2 (merosin)-deficient muscular dystrophy in a cat
por: Awamura, Yuichi, et al.
Publicado: (2008)

Bortezomib Does Not Reduce Muscular Dystrophy in the dy(2J)/dy(2J) Mouse Model of Laminin α2 Chain-Deficient Muscular Dystrophy
por: Körner, Zandra, et al.
Publicado: (2016)

An atypical expression of core α-Dystroglycan and Laminin-α2 in skin fibroblasts of patients with congenital muscular dystrophies
por: Sabry, Sahar, et al.
Publicado: (2023)

Magnetic Resonance Assessment of Hypertrophic and Pseudo-Hypertrophic Changes in Lower Leg Muscles of Boys with Duchenne Muscular Dystrophy and Their Relationship to Functional Measurements
por: Vohra, Ravneet S., et al.
Publicado: (2015)

Immobilization of Dystrophin and Laminin α2-Chain Deficient Zebrafish Larvae In Vivo Prevents the Development of Muscular Dystrophy
por: Li, Mei, et al.
Publicado: (2015)

Laminin α2 Deficiency-Related Muscular Dystrophy Mimicking Emery-Dreifuss and Collagen VI related Diseases
por: Nelson, Isabelle, et al.
Publicado: (2015)

Mesoangioblast delivery of miniagrin ameliorates murine model of merosin-deficient congenital muscular dystrophy type 1A
por: Domi, Teuta, et al.
Publicado: (2015)

Fukuyama Congenital Muscular Dystrophy
por: Agarwal, Amit, et al.
Publicado: (2022)

Respiratory and cardiac function in congenital muscular dystrophies with alpha dystroglycan deficiency
por: Pane, M., et al.
Publicado: (2012)

Diagnostic approach to the congenital muscular dystrophies
por: Bönnemann, Carsten G., et al.
Publicado: (2014)

Immortalized myogenic cells from congenital muscular dystrophy type1A patients recapitulate aberrant caspase activation in pathogenesis: a new tool for MDC1A research
por: Yoon, Soonsang, et al.
Publicado: (2013)

Congenital Muscular Dystrophy Due to Merosin Deficiency: Report of a New Mutation
por: Herrera Malpica, Wilmer Santiago, et al.
Publicado: (2023)

Autophagy increase in Merosin-Deficient Congenital Muscular Dystrophy type 1A
por: Mastrapasqua, Mariangela, et al.
Publicado: (2023)

Amelioration of muscle and nerve pathology of Lama2-related dystrophy by AAV9-laminin-αLN linker protein
por: McKee, Karen K., et al.
Publicado: (2022)

CDP-ribitol prodrug treatment ameliorates ISPD-deficient muscular dystrophy mouse model
por: Tokuoka, Hideki, et al.
Publicado: (2022)

Congenital Muscular Dystrophies: A Brief Review
por: Bertini, Enrico, et al.
Publicado: (2011)

Congenital muscular dystrophy with inflammation: Diagnostic considerations
por: Konkay, Kaumudi, et al.
Publicado: (2016)

Congenital muscular dystrophy: from muscle to brain
por: Falsaperla, Raffaele, et al.
Publicado: (2016)

Genetic and Clinical Advances of Congenital Muscular Dystrophy
por: Fu, Xiao-Na, et al.
Publicado: (2017)

Merosin-deficient congenital muscular dystrophy type 1A: A case report
por: HE, ZHANWEN, et al.
Publicado: (2013)

Novel LAMA2 Gene Mutations Associated with Merosin-Deficient Congenital Muscular Dystrophy
por: Hashemi-Gorji, Feyzollah, et al.
Publicado: (2018)

Amelioration of Muscle and Nerve Pathology in LAMA2 Muscular Dystrophy by AAV9-Mini-Agrin
por: Qiao, Chunping, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ddvlaj3tbvrv86sapjqdohobsp