An Evolutionary Approach for Identifying Driver Mutations in Colorectal Cancer

The traditional view of cancer as a genetic disease that can successfully be treated with drugs targeting mutant onco-proteins has motivated whole-genome sequencing efforts in many human cancer types. However, only a subset of mutations found within the genomic landscape of cancer is likely to provi...

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Detalles Bibliográficos
Autores principales: Foo, Jasmine, Liu, Lin L, Leder, Kevin, Riester, Markus, Iwasa, Yoh, Lengauer, Christoph, Michor, Franziska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575033/
https://www.ncbi.nlm.nih.gov/pubmed/26379039
http://dx.doi.org/10.1371/journal.pcbi.1004350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575033/
https://www.ncbi.nlm.nih.gov/pubmed/26379039
http://dx.doi.org/10.1371/journal.pcbi.1004350

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