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Changes in Brain Metallome/Metabolome Pattern due to a Single i.v. Injection of Manganese in Rats

Exposure to high concentrations of Manganese (Mn) is known to potentially induce an accumulation in the brain, leading to a Parkinson related disease, called manganism. Versatile mechanisms of Mn-induced brain injury are discussed, with inactivation of mitochondrial defense against oxidative stress...

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Detalles Bibliográficos
Autores principales: Neth, Katharina, Lucio, Marianna, Walker, Alesia, Zorn, Julia, Schmitt-Kopplin, Philippe, Michalke, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575095/
https://www.ncbi.nlm.nih.gov/pubmed/26383269
http://dx.doi.org/10.1371/journal.pone.0138270