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Changes in Brain Metallome/Metabolome Pattern due to a Single i.v. Injection of Manganese in Rats
Exposure to high concentrations of Manganese (Mn) is known to potentially induce an accumulation in the brain, leading to a Parkinson related disease, called manganism. Versatile mechanisms of Mn-induced brain injury are discussed, with inactivation of mitochondrial defense against oxidative stress...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575095/ https://www.ncbi.nlm.nih.gov/pubmed/26383269 http://dx.doi.org/10.1371/journal.pone.0138270 |