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Identification of Novel Aldose Reductase Inhibitors from Spices: A Molecular Docking and Simulation Study
Hyperglycemia in diabetic patients results in a diverse range of complications such as diabetic retinopathy, neuropathy, nephropathy and cardiovascular diseases. The role of aldose reductase (AR), the key enzyme in the polyol pathway, in these complications is well established. Due to notable side-e...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575143/ https://www.ncbi.nlm.nih.gov/pubmed/26384019 http://dx.doi.org/10.1371/journal.pone.0138186 |