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TBX1 Represses Vegfr2 Gene Expression and Enhances the Cardiac Fate of VEGFR2+ Cells

The T-box transcription factor TBX1 has critical roles in maintaining proliferation and inhibiting differentiation of cardiac progenitor cells of the second heart field (SHF). Haploinsufficiency of the gene that encodes it is a cause of congenital heart disease. Here, we developed an embryonic stem...

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Detalles Bibliográficos
Autores principales: Lania, Gabriella, Ferrentino, Rosa, Baldini, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575176/
https://www.ncbi.nlm.nih.gov/pubmed/26382615
http://dx.doi.org/10.1371/journal.pone.0138525