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Serum Sphingolipid Variations Associate with Hepatic Decompensation and Survival in Patients with Cirrhosis

BACKGROUND: Sphingolipids constitute bioactive molecules with functional implications in liver homeostasis. Particularly, ablation of very long chain ceramides in a knockout mouse model has been shown to cause a severe hepatopathy. METHODS: We aimed to evaluate the serum sphingolipid profile of 244...

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Detalles Bibliográficos
Autores principales: Grammatikos, Georgios, Ferreiròs, Nerea, Waidmann, Oliver, Bon, Dimitra, Schroeter, Sirkka, Koch, Alexander, Herrmann, Eva, Zeuzem, Stefan, Kronenberger, Bernd, Pfeilschifter, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575185/
https://www.ncbi.nlm.nih.gov/pubmed/26382760
http://dx.doi.org/10.1371/journal.pone.0138130