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Serum Sphingolipid Variations Associate with Hepatic Decompensation and Survival in Patients with Cirrhosis
BACKGROUND: Sphingolipids constitute bioactive molecules with functional implications in liver homeostasis. Particularly, ablation of very long chain ceramides in a knockout mouse model has been shown to cause a severe hepatopathy. METHODS: We aimed to evaluate the serum sphingolipid profile of 244...
Autores principales: | Grammatikos, Georgios, Ferreiròs, Nerea, Waidmann, Oliver, Bon, Dimitra, Schroeter, Sirkka, Koch, Alexander, Herrmann, Eva, Zeuzem, Stefan, Kronenberger, Bernd, Pfeilschifter, Josef |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575185/ https://www.ncbi.nlm.nih.gov/pubmed/26382760 http://dx.doi.org/10.1371/journal.pone.0138130 |
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