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Lung-derived exosome uptake into and epigenetic modulation of marrow progenitor/stem and differentiated cells

BACKGROUND: Our group has previously demonstrated that murine whole bone marrow cells (WBM) that internalize lung-derived extracellular vesicles (LDEVs) in culture express pulmonary epithelial cell–specific genes for up to 12 weeks. In addition, the lungs of lethally irradiated mice transplanted wit...

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Detalles Bibliográficos
Autores principales: Aliotta, Jason M., Pereira, Mandy, Sears, Edmund H., Dooner, Mark S., Wen, Sicheng, Goldberg, Laura R., Quesenberry, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575417/
https://www.ncbi.nlm.nih.gov/pubmed/26385657
http://dx.doi.org/10.3402/jev.v4.26166