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TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow
The cellular and molecular events that drive early innate lympoid cell (ILC) development remain poorly understood. We show that transcription factor TCF-1 is required for the efficient generation of all known adult ILC subsets and their precursors. Using novel reporter mice, we identified a new subs...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575643/ https://www.ncbi.nlm.nih.gov/pubmed/26280998 http://dx.doi.org/10.1038/ni.3248 |