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TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow

The cellular and molecular events that drive early innate lympoid cell (ILC) development remain poorly understood. We show that transcription factor TCF-1 is required for the efficient generation of all known adult ILC subsets and their precursors. Using novel reporter mice, we identified a new subs...

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Detalles Bibliográficos
Autores principales: Yang, Qi, Li, Fengyin, Harly, Christelle, Xing, Shaojun, Ye, Longyun, Xia, Xuefeng, Wang, Haikun, Wang, Xinxin, Yu, Shuyang, Zhou, Xinyuan, Cam, Maggie, Xue, Hai-Hui, Bhandoola, Avinash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575643/
https://www.ncbi.nlm.nih.gov/pubmed/26280998
http://dx.doi.org/10.1038/ni.3248