Clinical Safety and Immunogenicity of Tumor-Targeted, Plant-Made Id-KLH Conjugate Vaccines for Follicular Lymphoma

We report the first evaluation of plant-made conjugate vaccines for targeted treatment of B-cell follicular lymphoma (FL) in a Phase I safety and immunogenicity clinical study. Each recombinant personalized immunogen consisted of a tumor-derived, plant-produced idiotypic antibody (Ab) hybrid compris...

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Detalles Bibliográficos
Autores principales: Tusé, Daniel, Ku, Nora, Bendandi, Maurizio, Becerra, Carlos, Collins, Robert, Langford, Nyla, Sancho, Susana Inogés, López-Díaz de Cerio, Ascensión, Pastor, Fernando, Kandzia, Romy, Thieme, Frank, Jarczowski, Franziska, Krause, Dieter, Ma, Julian K.-C., Pandya, Shan, Klimyuk, Victor, Gleba, Yuri, Butler-Ransohoff, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575747/
https://www.ncbi.nlm.nih.gov/pubmed/26425548
http://dx.doi.org/10.1155/2015/648143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575747/
https://www.ncbi.nlm.nih.gov/pubmed/26425548
http://dx.doi.org/10.1155/2015/648143

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