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Conserved and divergent aspects of human T-cell development and migration in humanized mice
Humanized mice represent an important model to study the development and function of the human immune system. While it is known that mouse thymic stromal cells can support human T-cell development, the extent of interspecies cross-talk and the degree to which these systems recapitulate normal human...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575952/ https://www.ncbi.nlm.nih.gov/pubmed/25744551 http://dx.doi.org/10.1038/icb.2015.38 |