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Conserved and divergent aspects of human T-cell development and migration in humanized mice

Humanized mice represent an important model to study the development and function of the human immune system. While it is known that mouse thymic stromal cells can support human T-cell development, the extent of interspecies cross-talk and the degree to which these systems recapitulate normal human...

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Detalles Bibliográficos
Autores principales: Halkias, Joanna, Yen, Bonnie, Taylor, Kayleigh T, Reinhartz, Olaf, Winoto, Astar, Robey, Ellen A, Melichar, Heather J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575952/
https://www.ncbi.nlm.nih.gov/pubmed/25744551
http://dx.doi.org/10.1038/icb.2015.38