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A novel method to analyze 5-hydroxymethylcytosine in CpG sequences using maintenance DNA methyltransferase, DNMT1

Hydroxymethylcytosine has been shown to be involved in DNA demethylation and gene expression. Although methods to determine the position of hydroxymethylcytosine at single-base resolution have been reported, these methods involve some difficulties. Here, we report a simple method to analyze hydroxym...

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Detalles Bibliográficos
Autores principales: Takahashi, Saori, Suetake, Isao, Engelhardt, Jan, Tajima, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575954/
https://www.ncbi.nlm.nih.gov/pubmed/26504739
http://dx.doi.org/10.1016/j.fob.2015.09.003