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A novel method to analyze 5-hydroxymethylcytosine in CpG sequences using maintenance DNA methyltransferase, DNMT1
Hydroxymethylcytosine has been shown to be involved in DNA demethylation and gene expression. Although methods to determine the position of hydroxymethylcytosine at single-base resolution have been reported, these methods involve some difficulties. Here, we report a simple method to analyze hydroxym...
Autores principales: | Takahashi, Saori, Suetake, Isao, Engelhardt, Jan, Tajima, Shoji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575954/ https://www.ncbi.nlm.nih.gov/pubmed/26504739 http://dx.doi.org/10.1016/j.fob.2015.09.003 |
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