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Pharmacokinetics of Antituberculosis Drugs in HIV-Positive and HIV-Negative Adults in Malawi

Limited data address the impact of HIV coinfection on the pharmacokinetics (PK) of antituberculosis drugs in sub-Saharan Africa. A total of 47 Malawian adults underwent rich pharmacokinetic sampling at 0, 0.5, 1, 2, 3, 4, 6, 8, and 24 h postdose. Of the subjects, 51% were male, their mean age was 34...

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Detalles Bibliográficos
Autores principales: van Oosterhout, J. J., Dzinjalamala, F. K., Dimba, A., Waterhouse, D., Davies, G., Zijlstra, E. E., Molyneux, M. E., Molyneux, E. M., Ward, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576091/
https://www.ncbi.nlm.nih.gov/pubmed/26248378
http://dx.doi.org/10.1128/AAC.01193-15