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The Interaction between Cyclin B1 and Cytomegalovirus Protein Kinase pUL97 is Determined by an Active Kinase Domain

Replication of human cytomegalovirus (HCMV) is characterized by a tight virus-host cell interaction. Cyclin-dependent protein kinases (CDKs) are functionally integrated into viral gene expression and protein modification. The HCMV-encoded protein kinase pUL97 acts as a CDK ortholog showing structura...

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Detalles Bibliográficos
Autores principales: Steingruber, Mirjam, Socher, Eileen, Hutterer, Corina, Webel, Rike, Bergbrede, Tim, Lenac, Tihana, Sticht, Heinrich, Marschall, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576195/
https://www.ncbi.nlm.nih.gov/pubmed/26270673
http://dx.doi.org/10.3390/v7082834