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Structure and Biophysical Properties of a Triple-Stranded Beta-Helix Comprising the Central Spike of Bacteriophage T4

Gene product 5 (gp5) of bacteriophage T4 is a spike-shaped protein that functions to disrupt the membrane of the target cell during phage infection. Its C-terminal domain is a long and slender β-helix that is formed by three polypeptide chains wrapped around a common symmetry axis akin to three inte...

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Detalles Bibliográficos
Autores principales: Buth, Sergey A., Menin, Laure, Shneider, Mikhail M., Engel, Jürgen, Boudko, Sergei P., Leiman, Petr G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576200/
https://www.ncbi.nlm.nih.gov/pubmed/26295253
http://dx.doi.org/10.3390/v7082839