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Single-cell analysis reveals key roles for Bcl11a in regulating stem cell fate decisions

Cell-cycle fluctuations drive significant transcriptomic heterogeneity in murine hematopoietic stem cells. Additionally, deletion of Bcl11a alters the regulation of hematopoietic stem cell quiescence, self-renewal, and fate choice. Please see related Research article: http://www.genomebiology.com/20...

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Detalles Bibliográficos
Autores principales: Powers, Ashley N, Satija, Rahul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576375/
https://www.ncbi.nlm.nih.gov/pubmed/26390863
http://dx.doi.org/10.1186/s13059-015-0778-y