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Reconstruction of novel transcription factor regulons through inference of their binding sites

BACKGROUND: In most sequenced organisms the number of known regulatory genes (e.g., transcription factors (TFs)) vastly exceeds the number of experimentally-verified regulons that could be associated with them. At present, identification of TF regulons is mostly done through comparative genomics app...

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Detalles Bibliográficos
Autores principales: Elmas, Abdulkadir, Wang, Xiaodong, Samoilov, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576408/
https://www.ncbi.nlm.nih.gov/pubmed/26388177
http://dx.doi.org/10.1186/s12859-015-0685-y