Positive Modulation of the Glycine Receptor by Means of Glycine Receptor–Binding Aptamers

According to the gate control theory of pain, the glycine receptors (GlyRs) are putative targets for development of therapeutic analgesics. A possible approach for novel analgesics is to develop a positive modulator of the glycine-activated Cl(−) channels. Unfortunately, there has been limited succe...

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Detalles Bibliográficos
Autores principales: Shalaly, Nancy Dekki, Aneiros, Eduardo, Blank, Michael, Mueller, Johan, Nyman, Eva, Blind, Michael, Dabrowski, Michael A., Andersson, Christin V., Sandberg, Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576506/
https://www.ncbi.nlm.nih.gov/pubmed/26071243
http://dx.doi.org/10.1177/1087057115590575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576506/
https://www.ncbi.nlm.nih.gov/pubmed/26071243
http://dx.doi.org/10.1177/1087057115590575

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