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Positive Modulation of the Glycine Receptor by Means of Glycine Receptor–Binding Aptamers
According to the gate control theory of pain, the glycine receptors (GlyRs) are putative targets for development of therapeutic analgesics. A possible approach for novel analgesics is to develop a positive modulator of the glycine-activated Cl(−) channels. Unfortunately, there has been limited succe...
Autores principales: | Shalaly, Nancy Dekki, Aneiros, Eduardo, Blank, Michael, Mueller, Johan, Nyman, Eva, Blind, Michael, Dabrowski, Michael A., Andersson, Christin V., Sandberg, Kristian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576506/ https://www.ncbi.nlm.nih.gov/pubmed/26071243 http://dx.doi.org/10.1177/1087057115590575 |
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