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The Class I-Specific HDAC Inhibitor MS-275 Decreases Motivation to Consume Alcohol and Relapse in Heavy Drinking Rats

BACKGROUND: New strategies for the treatment of alcohol dependence are a pressing need, and recent evidence suggests that targeting enzymes involved in epigenetic mechanisms seems to have great potential. Among these mechanisms, alteration of histone acetylation by histone deacetylases is of great i...

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Detalles Bibliográficos
Autores principales: Jeanblanc, Jerome, Lemoine, Sandrine, Jeanblanc, Virginie, Alaux-Cantin, Stéphanie, Naassila, Mickaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576514/
https://www.ncbi.nlm.nih.gov/pubmed/25762717
http://dx.doi.org/10.1093/ijnp/pyv029