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Hippocampal-Dependent Antidepressant Action of the H(3) Receptor Antagonist Clobenpropit in a Rat Model of Depression
BACKGROUND: Histamine is a modulatory neurotransmitter regulating neuronal activity. Antidepressant drugs target modulatory neurotransmitters, thus ultimately regulating glutamatergic transmission and plasticity. Histamine H(3) receptor (H(3)R) antagonists have both pro-cognitive and antidepressant...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Oxford University Press
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576519/ https://www.ncbi.nlm.nih.gov/pubmed/25762718 http://dx.doi.org/10.1093/ijnp/pyv032 |