Fitness Trade-Offs Determine the Role of the Molecular Chaperonin GroEL in Buffering Mutations

Molecular chaperones fold many proteins and their mutated versions in a cell and can sometimes buffer the phenotypic effect of mutations that affect protein folding. Unanswered questions about this buffering include the nature of its mechanism, its influence on the genetic variation of a population,...

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Detalles Bibliográficos
Autores principales: Sabater-Muñoz, Beatriz, Prats-Escriche, Maria, Montagud-Martínez, Roser, López-Cerdán, Adolfo, Toft, Christina, Aguilar-Rodríguez, José, Wagner, Andreas, Fares, Mario A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576708/
https://www.ncbi.nlm.nih.gov/pubmed/26116858
http://dx.doi.org/10.1093/molbev/msv144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576708/
https://www.ncbi.nlm.nih.gov/pubmed/26116858
http://dx.doi.org/10.1093/molbev/msv144

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