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Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling

The receptor-interacting protein kinase 3 (RIPK3) plays crucial roles in programmed necrosis and innate inflammatory responses. However, a little is known about the involvement of RIPK3 in NKT cell-mediated immune responses. Here, we demonstrate that RIPK3 plays an essential role in NKT cell functio...

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Detalles Bibliográficos
Autores principales: Kang, Young Jun, Bang, Bo-Ram, Han, Kyung Ho, Hong, Lixin, Shim, Eun-Jin, Ma, Jianhui, Lerner, Richard A., Otsuka, Motoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576739/
https://www.ncbi.nlm.nih.gov/pubmed/26381214
http://dx.doi.org/10.1038/ncomms9371