α5β1 integrin recycling promotes Arp2/3-independent cancer cell invasion via the formin FHOD3

Invasive migration in 3D extracellular matrix (ECM) is crucial to cancer metastasis, yet little is known of the molecular mechanisms that drive reorganization of the cytoskeleton as cancer cells disseminate in vivo. 2D Rac-driven lamellipodial migration is well understood, but how these features app...

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Detalles Bibliográficos
Autores principales: Paul, Nikki R., Allen, Jennifer L., Chapman, Anna, Morlan-Mairal, Maria, Zindy, Egor, Jacquemet, Guillaume, Fernandez del Ama, Laura, Ferizovic, Nermina, Green, David M., Howe, Jonathan D., Ehler, Elisabeth, Hurlstone, Adam, Caswell, Patrick T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576860/
https://www.ncbi.nlm.nih.gov/pubmed/26370503
http://dx.doi.org/10.1083/jcb.201502040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576860/
https://www.ncbi.nlm.nih.gov/pubmed/26370503
http://dx.doi.org/10.1083/jcb.201502040

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