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BDNF modulates heart contraction force and long-term homeostasis through truncated TrkB.T1 receptor activation

Brain-derived neurotrophic factor (BDNF) is critical for mammalian development and plasticity of neuronal circuitries affecting memory, mood, anxiety, pain sensitivity, and energy homeostasis. Here we report a novel unexpected role of BDNF in regulating the cardiac contraction force independent of t...

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Detalles Bibliográficos
Autores principales: Fulgenzi, Gianluca, Tomassoni-Ardori, Francesco, Babini, Lucia, Becker, Jodi, Barrick, Colleen, Puverel, Sandrine, Tessarollo, Lino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576863/
https://www.ncbi.nlm.nih.gov/pubmed/26347138
http://dx.doi.org/10.1083/jcb.201502100