TRAIL(+) monocytes and monocyte-related cells cause lung damage and thereby increase susceptibility to influenza–Streptococcus pneumoniae coinfection

Streptococcus pneumoniae coinfection is a major cause of influenza-associated mortality; however, the mechanisms underlying pathogenesis or protection remain unclear. Using a clinically relevant mouse model, we identify immune-mediated damage early during coinfection as a new mechanism causing susce...

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Detalles Bibliográficos
Autores principales: Ellis, Gregory T, Davidson, Sophia, Crotta, Stefania, Branzk, Nora, Papayannopoulos, Venizelos, Wack, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576987/
https://www.ncbi.nlm.nih.gov/pubmed/26265006
http://dx.doi.org/10.15252/embr.201540473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576987/
https://www.ncbi.nlm.nih.gov/pubmed/26265006
http://dx.doi.org/10.15252/embr.201540473

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