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Focal Ischemic Injury with Complex Middle Cerebral Artery in Stroke-Prone Spontaneously Hypertensive Rats with Loss-Of-Function in NADPH Oxidases

By means of introgressing a loss-of-function mutation in the p22phox gene from the Matsumoto Eosinophilia Shinshu (MES) rat to stroke-prone spontaneously hypertensive rats (SHRSP), we constructed the SHRSP-based congenic strain lacking the P22PHOX expression (i.e., lacking NADPH oxidases [NOX] activ...

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Detalles Bibliográficos
Autores principales: Yao, Hiroshi, Ferdaus, Mohammed Zubaerul, Zahid, Hasan Md., Ohara, Hiroki, Nakahara, Tatsuo, Nabika, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577106/
https://www.ncbi.nlm.nih.gov/pubmed/26389812
http://dx.doi.org/10.1371/journal.pone.0138551