The transcription factor XBP1 is selectively required for eosinophil differentiation

The transcription factor XBP1 has been linked to the development of highly secretory tissues such as plasma cells and Paneth cells, yet its function in granulocyte maturation has remained unknown. Here we discovered an unexpectedly selective and absolute requirement for XBP1 in eosinophil differenti...

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Detalles Bibliográficos
Autores principales: Bettigole, Sarah E., Lis, Raphael, Adoro, Stanley, Lee, Ann-Hwee, Spencer, Lisa A., Weller, Peter F., Glimcher, Laurie H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577297/
https://www.ncbi.nlm.nih.gov/pubmed/26147683
http://dx.doi.org/10.1038/ni.3225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577297/
https://www.ncbi.nlm.nih.gov/pubmed/26147683
http://dx.doi.org/10.1038/ni.3225

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