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The transcription factor XBP1 is selectively required for eosinophil differentiation
The transcription factor XBP1 has been linked to the development of highly secretory tissues such as plasma cells and Paneth cells, yet its function in granulocyte maturation has remained unknown. Here we discovered an unexpectedly selective and absolute requirement for XBP1 in eosinophil differenti...
Autores principales: | Bettigole, Sarah E., Lis, Raphael, Adoro, Stanley, Lee, Ann-Hwee, Spencer, Lisa A., Weller, Peter F., Glimcher, Laurie H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577297/ https://www.ncbi.nlm.nih.gov/pubmed/26147683 http://dx.doi.org/10.1038/ni.3225 |
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