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Kainic Acid-Induced Golgi Complex Fragmentation/Dispersal Shifts the Proteolysis of Reelin in Primary Rat Neuronal Cells: An In Vitro Model of Early Stage Epilepsy

The endoplasmic reticulum-lysosome-Golgi network plays an important role in Reelin glycosylation and its proteolytic processing. Golgi complex fragmentation is associated with the separation of Reelin from this network. Kainic acid (KA) is an excitotoxic agent commonly used to induce epilepsy in rod...

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Detalles Bibliográficos
Autores principales: Kaneko, Yuji, Sullivan, Robert, Dailey, Travis, Vale, Fernando L., Tajiri, Naoki, Borlongan, Cesar V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577368/
https://www.ncbi.nlm.nih.gov/pubmed/25790952
http://dx.doi.org/10.1007/s12035-015-9126-1