Cargando…

Kainic Acid-Induced Golgi Complex Fragmentation/Dispersal Shifts the Proteolysis of Reelin in Primary Rat Neuronal Cells: An In Vitro Model of Early Stage Epilepsy

The endoplasmic reticulum-lysosome-Golgi network plays an important role in Reelin glycosylation and its proteolytic processing. Golgi complex fragmentation is associated with the separation of Reelin from this network. Kainic acid (KA) is an excitotoxic agent commonly used to induce epilepsy in rod...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kaneko, Yuji, Sullivan, Robert, Dailey, Travis, Vale, Fernando L., Tajiri, Naoki, Borlongan, Cesar V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577368/ https://www.ncbi.nlm.nih.gov/pubmed/25790952 http://dx.doi.org/10.1007/s12035-015-9126-1

Ejemplares similares

Stem Cell Transplantation for Neuroprotection in Stroke
por: Shinozuka, Kazutaka, et al.
Publicado: (2013)

Addendum: Shinozuka, K. et al. Stem Cell Transplantation for Neuroprotection in Stroke. Brain Sci. 2013, 3, 239–261
por: Shinozuka, Kazutaka, et al.
Publicado: (2017)

Reelin Proteolysis Affects Signaling Related to Normal Synapse Function and Neurodegeneration
por: Lussier, April L., et al.
Publicado: (2016)

An Update on Translating Stem Cell Therapy for Stroke from Bench to Bedside
por: Dailey, Travis, et al.
Publicado: (2013)

Cyclosporine A Treatment Abrogates Ischemia‐Induced Neuronal Cell Death by Preserving Mitochondrial Integrity through Upregulation of the Parkinson's Disease‐Associated Protein DJ‐1
por: Tajiri, Naoki, et al.
Publicado: (2016)

The Kainic Acid Models of Temporal Lobe Epilepsy
por: Rusina, Evgeniia, et al.
Publicado: (2021)

Considering the Role of Extracellular Matrix Molecules, in Particular Reelin, in Granule Cell Dispersion Related to Temporal Lobe Epilepsy
por: Leifeld, Jennifer, et al.
Publicado: (2022)

Oxygen–Glucose‐Deprived Rat Primary Neural Cells Exhibit DJ‐1 Translocation into Healthy Mitochondria: A Potent Stroke Therapeutic Target
por: Kaneko, Yuji, et al.
Publicado: (2013)

Oxytocin modulates GABA(A)R subunits to confer neuroprotection in stroke in vitro
por: Kaneko, Yuji, et al.
Publicado: (2016)

Antiepileptic effects of exogenous β-hydroxybutyrate on kainic acid-induced epilepsy
por: Si, Jianping, et al.
Publicado: (2020)

Covalent fragment inhibits intramembrane proteolysis
por: Eden, Angela, et al.
Publicado: (2022)

Combination Treatment of Hypothermia and Mesenchymal Stromal Cells Amplifies Neuroprotection in Primary Rat Neurons Exposed to Hypoxic-Ischemic-Like Injury In Vitro: Role of the Opioid System
por: Kaneko, Yuji, et al.
Publicado: (2012)

Intravenous Bone Marrow Stem Cell Grafts Preferentially Migrate to Spleen and Abrogate Chronic Inflammation in Stroke
por: Acosta, Sandra A., et al.
Publicado: (2015)

Altered Balance of Reelin Proteolytic Fragments in the Cerebrospinal Fluid of Alzheimer’s Disease Patients
por: Lopez-Font, Inmaculada, et al.
Publicado: (2022)

Reelin Signaling Pathway and Mesial Temporal Lobe Epilepsy: A Causative Link
por: Gupta, Tulika, et al.
Publicado: (2023)

Neurodegeneration and histochemical plasticity in the rat subiculum after kainic acid-induced epilepsy
por: Drexel, Meinrad, et al.
Publicado: (2011)

Dynamic Expression of CX36 Protein in Kainic Acid Kindling induced Epilepsy
por: Wu, Xue-mei, et al.
Publicado: (2017)

The role of DJ-1 in the oxidative stress cell death cascade after stroke
por: Pantcheva, Paolina, et al.
Publicado: (2014)

Delta Opioid Receptor and Its Peptide: A Receptor-Ligand Neuroprotection
por: Staples, Meaghan, et al.
Publicado: (2013)

Increased Amyloid Precursor Protein and Tau Expression Manifests as Key Secondary Cell Death in Chronic Traumatic Brain Injury
por: Acosta, Sandra A., et al.
Publicado: (2016)

Seizure-Induced Motility of Differentiated Dentate Granule Cells Is Prevented by the Central Reelin Fragment
por: Orcinha, Catarina, et al.
Publicado: (2016)

The real role of reelin
por: Wells, William A.
Publicado: (2002)

Reelin and Neuropsychiatric Disorders
por: Ishii, Kazuhiro, et al.
Publicado: (2016)

The clinical phenotype of autosomal dominant lateral temporal lobe epilepsy related to reelin mutations
por: Michelucci, Roberto, et al.
Publicado: (2017)

Golgi fragmentation in Alzheimer's disease
por: Joshi, Gunjan, et al.
Publicado: (2015)

Neurodegeneration and plastic changes in parahippocampal regions of the rat after kainic acid-induced epilepsy
por: Drexel, Meinrad, et al.
Publicado: (2008)

Targeting the Mouse Ventral Hippocampus in the Intrahippocampal Kainic Acid Model of Temporal Lobe Epilepsy
por: Zeidler, Zachary, et al.
Publicado: (2018)

Neuroprotective effects of trigonelline in kainic acid-induced epilepsy: Behavioral, biochemical, and functional insights
por: Faizan, Mohammad, et al.
Publicado: (2023)

Fragmentation of Golgi complex and Golgi autoantigens during apoptosis and necrosis
por: Nozawa, Kazuhisa, et al.
Publicado: (2002)

Immediate, but Not Delayed, Microsurgical Skull Reconstruction Exacerbates Brain Damage in Experimental Traumatic Brain Injury Model
por: Glover, Loren E., et al.
Publicado: (2012)

Brain Region‐Specific Histopathological Effects of Varying Trajectories of Controlled Cortical Impact Injury Model of Traumatic Brain Injury
por: Pabón, Mibel M., et al.
Publicado: (2016)

EpCAM proteolysis: new fragments with distinct functions?
por: Schnell, Ulrike, et al.
Publicado: (2013)

Physiological significance of proteolytic processing of Reelin revealed by cleavage-resistant Reelin knock-in mice
por: Okugawa, Eisuke, et al.
Publicado: (2020)

Peripheral Nerve Injury: Stem Cell Therapy and Peripheral Nerve Transfer
por: Sullivan, Robert, et al.
Publicado: (2016)

Resting state functional network disruptions in a kainic acid model of temporal lobe epilepsy
por: Gill, Ravnoor Singh, et al.
Publicado: (2016)

Compensatory Mechanisms Modulate the Neuronal Excitability in a Kainic Acid-Induced Epilepsy Mouse Model
por: Pan, Gaojie, et al.
Publicado: (2018)

Disrupted female estrous cyclicity in the intrahippocampal kainic acid mouse model of temporal lobe epilepsy
por: Li, Jiang, et al.
Publicado: (2016)

The potential neuroprotective roles of olive leaf extract in an epilepsy rat model induced by kainic acid
por: Khamse, Safoura, et al.
Publicado: (2020)

Diurnal burden of spontaneous seizures in early epileptogenesis in the post‐kainic acid rat model of epilepsy
por: Mizuno, Stephanie, et al.
Publicado: (2021)

Tau Proteolysis in the Pathogenesis of Tauopathies: Neurotoxic Fragments and Novel Biomarkers
por: Quinn, James P., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_qo0ejlmmguue1rmjfthl0a1pe2