Generating Virtual Patients by Multivariate and Discrete Re-Sampling Techniques

PURPOSE: Clinical Trial Simulations (CTS) are a valuable tool for decision-making during drug development. However, to obtain realistic simulation scenarios, the patients included in the CTS must be representative of the target population. This is particularly important when covariate effects exist...

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Detalles Bibliográficos
Autores principales: Teutonico, D., Musuamba, F., Maas, H. J., Facius, A., Yang, S., Danhof, M., Della Pasqua, O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577546/
https://www.ncbi.nlm.nih.gov/pubmed/25994981
http://dx.doi.org/10.1007/s11095-015-1699-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577546/
https://www.ncbi.nlm.nih.gov/pubmed/25994981
http://dx.doi.org/10.1007/s11095-015-1699-x

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