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Phosphorylation of Izumo1 and its role in male infertility

Izumo1 is a testis-specific gene product, whose function is essential for sperm-egg fusion. Throughout its lifespan, Izumo1 is posttranslationally modified, being both N-linked glycosylated on its extracellular domain and phosphorylated on the intracellular C-terminal tail. Within the caput regions...

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Detalles Bibliográficos
Autores principales: Young, Samantha AM, Aitken, John, Baker, Mark A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577576/
https://www.ncbi.nlm.nih.gov/pubmed/25994654
http://dx.doi.org/10.4103/1008-682X.156119